Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Role of Cerebellum and Prefrontal Cortex in Memory

Role of Cerebellum and Prefrontal Cortex in Memory

The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Postconcussion physical activity frequency and plasma biomarker associations among adolescents.

Journal of neurosurgery. Pediatrics·2026

Same author

Concussion Symptom Resolution Expectations and Subsequent Development of Persisting Symptoms After Adolescent Concussion.

Journal of athletic training·2026

Same author

Evaluating Associations Between Postconcussion Physical Activity and Brain Neurometabolite Concentrations in the Posterior Cingulate Gyrus.

Journal of child neurology·2026

Same author

The Integrated Effect of Physical Activity and Sleep Problems on Concussion Symptom Resolution.

Journal of sport rehabilitation·2026

Same author

Task-specific plantar pressure adaptations in individuals with patellofemoral pain syndrome during dynamic activities: a systematic review.

Sports biomechanics·2026

Same author

Sex Differences in Physical Activity and Energy Expenditure after Adolescent Concussion.

Medicine and science in sports and exercise·2026

Search research articles

Related Experiment Video

Updated: Mar 2, 2026

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury

Published on: November 19, 2012

Cortical and Physical Function after Mild Traumatic Brain Injury.

Alia L Yasen¹, David R Howell, Li-Shan Chou

¹1Department of Human Physiology, University of Oregon, Eugene, OR; 2Division of Sports Medicine, Department of Orthopedics, Children's Hospital Boston, Boston, MA; 3The Micheli Center for Sports Injury Prevention, Waltham, MA; and 4Education Development Center, Inc., Waltham, MA.

Medicine and Science in Sports and Exercise

|May 17, 2017

Summary

Mild traumatic brain injury (mTBI) impairs cognitive and motor functions. However, intracortical inhibition levels did not predict functional recovery in mTBI patients. This finding is crucial for understanding mTBI recovery patterns.

More Related Videos

Controlled Cortical Impact Model of Mouse Brain Injury with Therapeutic Transplantation of Human Induced Pluripotent Stem Cell-Derived Neural Cells

Controlled Cortical Impact Model of Mouse Brain Injury with Therapeutic Transplantation of Human Induced Pluripotent Stem Cell-Derived Neural Cells

Published on: July 10, 2019

Controlled Cortical Impact Model for Traumatic Brain Injury

Controlled Cortical Impact Model for Traumatic Brain Injury

Published on: August 5, 2014

Related Experiment Videos

Last Updated: Mar 2, 2026

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury

Published on: November 19, 2012

Controlled Cortical Impact Model of Mouse Brain Injury with Therapeutic Transplantation of Human Induced Pluripotent Stem Cell-Derived Neural Cells

Controlled Cortical Impact Model of Mouse Brain Injury with Therapeutic Transplantation of Human Induced Pluripotent Stem Cell-Derived Neural Cells

Published on: July 10, 2019

Controlled Cortical Impact Model for Traumatic Brain Injury

Controlled Cortical Impact Model for Traumatic Brain Injury

Published on: August 5, 2014

Area of Science:

Neuroscience
Traumatology
Rehabilitation Medicine

Background:

Mild traumatic brain injury (mTBI) is a common neurological condition with potential long-term cognitive and motor deficits.
Intracortical inhibition, a measure of neural pathway regulation, is hypothesized to play a role in post-injury recovery.
Understanding the relationship between intracortical inhibition and functional recovery is vital for developing targeted rehabilitation strategies.

Purpose of the Study:

To prospectively investigate the association between intracortical inhibition and functional recovery in individuals following mild traumatic brain injury (mTBI).
To determine if measures of intracortical inhibition, specifically cortical silent period (CSP) duration, correlate with cognitive and motor function recovery post-mTBI.

Main Methods:

A prospective study involving 20 individuals with mTBI and 20 matched controls.
Utilized transcranial magnetic stimulation to measure cortical silent period (CSP) duration.
Assessed cognitive function using the Attentional Network Test and motor function via gait analysis at multiple time points post-injury.

Main Results:

Individuals with mTBI exhibited prolonged reaction times and slower dual-task walking speeds acutely after injury compared to controls.
Cortical silent period (CSP) duration tended to be longer in the mTBI group at 72 hours post-injury.
Changes in CSP duration over time were not significantly associated with improvements in reaction time or walking speeds.

Conclusions:

Cognitive and motor functions were significantly impaired in the mTBI group in the acute phase.
Despite acute impairments, intracortical inhibition levels were not found to be associated with the degree of functional recovery in either cognitive or motor domains.
These findings suggest that intracortical inhibition may not be a primary predictor of functional recovery trajectories after mild traumatic brain injury.