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Related Experiment Video

Updated: Mar 2, 2026

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Herbs in Oral Mucositis.

Maryam Baharvand1, Soudeh Jafari2, Hamed Mortazavi3

  • 1Professor, Department of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Journal of Clinical and Diagnostic Research : JCDR
|May 18, 2017
PubMed
Summary

Herbal medicine offers a promising approach to manage oral mucositis, a painful side effect of cancer treatments. This review explores natural remedies for preventing and treating this condition with fewer side effects.

Keywords:
ChemotherapyMedicinal plantNeoplasmsRadiotherapyStomatitis

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Area of Science:

  • Oncology
  • Pharmacology
  • Integrative Medicine

Background:

  • Oral mucositis (OM) is a debilitating inflammatory condition affecting the oral mucosa, often caused by chemotherapy and radiation therapy.
  • Severe OM significantly impacts patients' quality of life and can lead to treatment delays or cessation due to infection or systemic complications.
  • Current management strategies for OM are limited, prompting interest in alternative and complementary therapies.

Purpose of the Study:

  • To review the preventive and therapeutic applications of herbal medicine for alleviating oral mucositis.
  • To explore the various mechanisms of action through which herbal agents may combat OM.
  • To highlight the potential of natural compounds in managing OM symptoms and improving patient outcomes.

Main Methods:

  • Systematic literature search for studies on herbal medicine and oral mucositis.
  • Analysis of identified studies focusing on preventive and therapeutic interventions.
  • Evaluation of the proposed mechanisms of action for herbal remedies in OM management.

Main Results:

  • Herbal medicines demonstrate diverse therapeutic properties including antioxidant, analgesic, anti-inflammatory, antifungal, and antiseptic activities relevant to OM.
  • Several natural agents found in plants show potential in mitigating OM symptoms through various interventions.
  • The use of herbs is gaining attention due to their favorable side effect profile compared to conventional pharmaceutical agents.

Conclusions:

  • Herbal medicine presents a viable option for the prevention and treatment of oral mucositis.
  • Natural agents may offer a safer alternative for managing OM, reducing treatment-related toxicities.
  • Further research into specific herbal compounds and their efficacy in OM is warranted.