Related Experiment Video
Updated: Mar 2, 2026
Mouse Round Spermatid Injection
Published on: January 26, 2024
Onco-testicular sperm extraction (onco-TESE) for bilateral testicular tumors: two case reports
Sohgo Tsutsumi1,2, Takashi Kawahara3, Teppei Takeshima2
1Department of Urology/Renal Transplantation, Yokohama City University Medical Center, Yokohama, Japan.
Background:
Most patients with testicular cancer are infertile; thus, the preservation of the sperm after surgery is an important factor to consider. We report two cases of bilateral testicular cancer in patients who underwent bilateral higher orchiectomy and simultaneous testicular sperm extraction.
Case Presentation:
Two Asian-Japanese men were referred to our hospital with bilateral testicular tumors. Both of the patients were preoperatively diagnosed with azoospermia and requested testicular sperm extraction at the time of higher orchiectomy. In one patient, sperm was successfully harvested and then frozen. In the other patient, sperm could not be retrieved from the patient's testis. In both patients, the pathological diagnosis was seminoma. Testicular tumors often occur in patients of reproductive age. The preservation of sperm before chemotherapy or bilateral orchiectomy is necessary for patients with testicular tumors who wish to be fathers.
Conclusions:
Onco-testicular sperm extraction might be an option for patients with testicular cancer and azoospermia or severe oligospermia.
