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IgG4-Aortopathy: An Underappreciated Cause of Non-Infectious Thoracic Aortitis
Victor Aguirre1, Catherine Connolly1, Robert Stuklis1
1Cardiothoracic Surgical Unit, Royal Adelaide Hospital, Adelaide, SA, Australia.
Abstract:
IgG4 related thoracic aortitis is a recent addition to the differential diagnosis for inflammatory aortic disease - a condition which is often underappreciated until complications arise such as aneurysmal formation or aortic dissection. Currently, IgG4 aortitis remains a post-surgical diagnosis reliant on positive immunohistochemistry findings. Management is guided by the extent of disease involvement, which can be gauged by serum IgG4 levels and radiological findings. Options include surgical resection, corticosteroid therapy and steroid-sparing agents to prevent relapses.
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