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Association of PECAM-1 Gene Polymorphisms with Kawasaki Disease in Chinese Children
Zhuoying Li1, Dong Han1, Jie Jiang1
1Department of Pediatrics, The Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, China.
Abstract:
Kawasaki disease (KD) is an acute systemic vasculitis complicated by development of coronary artery lesions. PECAM-1 is a kind of cell adhesion molecule, which plays an important role in coronary artery disease. The relationship between PECAM-1 gene polymorphisms and their susceptibility to Kawasaki diseases (KD) is still unclear. In our study, we examined the PECAM-1 gene polymorphisms in 44 KD patients and 59 healthy children and revealed the correlation of PECAM-1 gene polymorphisms in KD children with and without coronary artery lesions (CAL).
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