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Pacing Induced Ventricular Dysfunction in a Child: Improvement with Reduction in Paced Rate
Shilpi Garg1, Seshadri Balaji2
1Division of Cardiology, Department of Pediatrics, Oregon Health & Science University, 3181 SW Sam Jackson Rd, Portland, OR, 97239, USA. gargs@ohsu.edu.
Pediatric Cardiology
|May 18, 2017
Summary
Right ventricular pacing can impair left ventricular function. Reducing pacing rate in an infant with RV-pacing induced cardiomyopathy improved function, highlighting the rate-dysfunction link.
Area of Science:
- Cardiology
- Electrophysiology
- Pediatric Cardiology
Background:
- Right ventricular (RV) pacing is linked to impaired left ventricular (LV) function via electrical dyssynchrony and myocardial remodeling.
- Existing strategies like biventricular pacing or LV lead placement can reverse RV-pacing induced dysfunction.
Observation:
- This study presents a case of an infant diagnosed with RV-pacing induced cardiomyopathy.
- The infant's condition showed improvement when the pacing rate was decreased.
Findings:
- A direct relationship exists between pacing rate and the development of LV dysfunction.
- Reducing the pacing rate in this infant led to a measurable improvement in LV function.
Implications:
- Pacing rate is a critical factor in managing RV-pacing induced cardiomyopathy.
- Adjusting pacing parameters may offer a therapeutic strategy for similar pediatric cases.
- Further research into optimizing pacing strategies is warranted to prevent or mitigate LV dysfunction.
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