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Published on: July 12, 2024
An audit of adherence to heart failure guidelines in an Australian hospital: A pharmacist perspective
Viviane Khalil1,2, Melanie Danninger3, Wei Wang4
1Pharmacy Department, Frankston Hospital, Frankston, Australia.
Insights
Many chronic heart failure patients are not prescribed evidence-based therapy (EBT) upon discharge. Cardiac ward patients and those with pharmacist input received more guideline-adherent care, highlighting areas for improvement.
Area of Science:
- Cardiology
- Pharmacology
- Health Services Research
Background:
- Chronic heart failure (CHF) management guidelines aim to optimize patient outcomes.
- Adherence to evidence-based therapy (EBT) is crucial for effective CHF care.
- Gaps between guidelines and clinical practice require investigation.
Purpose of the Study:
- To determine the proportion of CHF patients discharged with EBT at an Australian hospital.
- To identify factors influencing EBT prescribing for CHF.
- To compare EBT rates between cardiac and medical wards and explore the pharmacist's role.
Main Methods:
- Retrospective audit of 6 months of consecutive CHF patient medical records.
- Analysis of prescribing patterns at hospital discharge.
- Comparison of prescribing based on ward type and pharmacist involvement.
Main Results:
- Only 52% of patients received ACE inhibitors/ARBs, 49% beta-blockers, and 15% aldosterone antagonists at discharge.
- Prescribing contraindications and comorbidities were key determinants of EBT.
- Higher EBT rates were observed in patients discharged from cardiac wards and those with pharmacist review.
Conclusions:
- Significant discrepancies exist between national CHF guidelines and current prescribing practices.
- Discharge from cardiac wards is associated with increased guideline adherence.
- Pharmacist interventions can improve EBT prescribing for CHF patients, closing practice gaps.
Rationale, Aims, And Objectives:
The Australian National Heart Foundation Guidelines have been developed to guide clinicians on how to best manage chronic heart failure (CHF) patients according to the current best available evidence. The primary aim of this study is to evaluate the proportion of patients prescribed evidence-based therapy (EBT) for CHF on discharge at this Australian metropolitan hospital and factors affecting its prescribing. The secondary aims are to examine the proportion of patients prescribed EBT on discharge on cardiac wards compared to medical wards and to explore the role of the pharmacist in the management of these patients.
Method:
A retrospective audit of patients' medical notes who were admitted consecutively for CHF management was conducted over 6 months to examine their management.
Results:
The results showed at discharge, a total of 52% of patients were discharged on angiotensin converting enzyme inhibitors/angiotensin receptor blockers, 49% were discharged on β-blockers, 15% were on Aldosterone receptor antagonists, 90% were discharged on diuretics, and 29% were discharged on Digoxin. The main determinants of prescribing EBT on discharge were the presence of prescribing contraindications and patients' comorbidities. Patients discharged from cardiac wards were more likely to be prescribed EBT than if discharged on medical wards. Furthermore, in the subset of the cohort who was reviewed by a pharmacist during admission, a higher percentage of patients were discharged on EBT compared with those who did not have a pharmaceutical input.
Conclusion:
This study highlighted existing gaps between the National CHF Guidelines and clinical prescribing practice in this hospital. Patients who were discharged from cardiac wards were more likely to be prescribed medications concordant with the guidelines, and there is further opportunity for pharmacists to assist in closing gaps in prescribing practice by the promotion of adherence to these guidelines.
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