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Updated: Mar 2, 2026

Screening Sperm for the Rapid Isolation of Germline Edits in Zebrafish
Published on: February 10, 2023
[What if the sperm donor has a hereditary disease? Informed consent needed for sharing medical information]
J J van der Smagt1, L C Govaerts, S G M Frints
1UMC Utrecht, afd. Medische Genetica, Utrecht.
Abstract:
There are no regulations in the Netherlands regarding the exchange of important genetic information that has become available after the birth of a child conceived with donor gametes. This may lead to difficult situations such as when the gamete donor is found to suffer from a genetic cancer-predisposition disorder. Genetic information about the donor that becomes available later may be of great importance to donor offspring. Genetic information uncovered in the donor child may likewise be of importance to legal offspring of the gamete donor. We propose an informed-consent procedure for both donors and recipients to take better care of this issue.
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