Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

MOS Capacitor01:25

MOS Capacitor

1.7K
A Metal-Oxide-Semiconductor (MOS) capacitor is a fundamental structure used extensively in semiconductor device technology, particularly in the fabrication of integrated circuits and MOSFETs (metal-oxide-semiconductor field-effect transistors). The MOS capacitor consists of three layers: a metal gate, a dielectric oxide, and a semiconductor substrate.
The metal gate is typically made from highly conductive materials such as aluminum or polysilicon. Beneath the metal gate lies a thin layer of...
1.7K
Ligand-Gated Ion Channel Receptor: Gating Mechanism01:30

Ligand-Gated Ion Channel Receptor: Gating Mechanism

4.4K
Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...
4.4K
Electrochemical Gradient and Channel Proteins: An Overview01:21

Electrochemical Gradient and Channel Proteins: An Overview

4.9K
An electrochemical gradient is a fundamental concept in biology and chemistry. It regulates the movement of ions across cell membranes. This movement is influenced by two factors:
The electrical gradient: The electrical gradient across cell membranes refers to the difference in electric charge between the inside and outside of a cell.  This difference drives the movement of ions towards or away from the cells. For instance, if the inside of the cell is more negatively charged relative to...
4.9K
Electrochemical Systems01:24

Electrochemical Systems

19
Electrochemical systems provide a fascinating insight into the dynamic interplay of charged species within various phases. One notable example is the interaction between a membrane permeable to K⁺ ions but not to Cl⁻ ions, separating an aqueous KCl solution from pure water. As K⁺ ions diffuse through the membrane, they generate net charges on each phase, leading to a potential difference between them.Similarly, when a piece of Zn is immersed in an aqueous ZnSO₄ solution,...
19

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Roles of astrocytic Connexin 43 gap junctional deficit in alpha-synucleinopathy and inflammation relevant to Parkinson's.

Experimental neurology·2026
Same author

Brain-computer interfaces and neuroprosthetics in the next era of neurosurgery.

British journal of neurosurgery·2026
Same author

ADVANTAGE: Advanced discovery of visceral analgesics by neuroimmune targets and the genetics of extreme human phenotype, a study protocol.

PloS one·2026
Same author

Thermodynamic Limits to Molecular Doping in Conjugated Polymers: A Perspective on Phase Behavior and Miscibility.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Biomimetic metamaterial-based interface for decoding heterogeneous mechanodermal activity.

Science advances·2026
Same author

Author Correction: Control of spatiotemporal activation of organ-specific fibers in the swine vagus nerve by intermittent interferential current stimulation.

Nature communications·2026

Related Experiment Video

Updated: Mar 2, 2026

Assembly and Characterization of Biomolecular Memristors Consisting of Ion Channel-doped Lipid Membranes
08:07

Assembly and Characterization of Biomolecular Memristors Consisting of Ion Channel-doped Lipid Membranes

Published on: March 9, 2019

8.4K

Neuromorphic device architectures with global connectivity through electrolyte gating.

Paschalis Gkoupidenis1, Dimitrios A Koutsouras1, George G Malliaras1

  • 1Department of Bioelectronics, Ecole Nationale Supérieure des Mines, CMP-EMSE, MOC, Gardanne 13541, France.

Nature Communications
|May 18, 2017
PubMed
Summary
This summary is machine-generated.

This study demonstrates global regulation in neuromorphic devices using an electrolyte, mimicking brain homeoplasticity. This approach enables complex network behaviors with reduced hardwired connections, advancing neuromorphic engineering.

More Related Videos

Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits
10:32

Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits

Published on: April 15, 2015

8.9K
A Multi-compartment CNS Neuron-glia Co-culture Microfluidic Platform
13:24

A Multi-compartment CNS Neuron-glia Co-culture Microfluidic Platform

Published on: September 10, 2009

12.4K

Related Experiment Videos

Last Updated: Mar 2, 2026

Assembly and Characterization of Biomolecular Memristors Consisting of Ion Channel-doped Lipid Membranes
08:07

Assembly and Characterization of Biomolecular Memristors Consisting of Ion Channel-doped Lipid Membranes

Published on: March 9, 2019

8.4K
Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits
10:32

Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits

Published on: April 15, 2015

8.9K
A Multi-compartment CNS Neuron-glia Co-culture Microfluidic Platform
13:24

A Multi-compartment CNS Neuron-glia Co-culture Microfluidic Platform

Published on: September 10, 2009

12.4K

Area of Science:

  • Neuromorphic Engineering
  • Neuroscience
  • Materials Science

Background:

  • Brain information processing relies on neural networks with global regulation (homeoplasticity).
  • Existing neuromorphic devices lack effective global regulation mechanisms.
  • Homeoplasticity's role in neural ensembles is crucial but underexplored in artificial systems.

Purpose of the Study:

  • To demonstrate global control in neuromorphic devices using an electrolyte.
  • To mimic homeoplasticity phenomena observed in biological neural environments.
  • To explore electrolyte-mediated complex connections for advanced neuromorphic functions.

Main Methods:

  • Fabrication of organic devices using poly(3,4-ethylenedioxythiophene):poly(styrene sulf) immersed in an electrolyte.
  • Implementation of electrolyte gating for global control of device arrays.
  • Analysis of device behavior mimicking biological neural network coupling and coincidence detection.

Main Results:

  • Achieved global regulation of an array of organic neuromorphic devices via electrolyte immersion.
  • Demonstrated behavior reminiscent of local activity and global oscillations coupling in neural networks.
  • Showcased electrolyte-induced complex inter-device connections enabling coincidence detection.

Conclusions:

  • Electrolyte gating effectively mimics biological homeoplasticity in neuromorphic devices.
  • This approach facilitates complex network behaviors with minimal hardwired connectivity.
  • Electrolyte-mediated interactions offer a promising pathway for advanced, scalable neuromorphic systems.