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Updated: Mar 2, 2026
Isolation and Quantification of Zika Virus from Multiple Organs in a Mouse
Published on: August 15, 2019
Zika virus isolation from semen
Elena Percivalle1, Maurizio Zavattoni1, Fausto Fausto1,2
1Microbiology and Virology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Abstract:
Zika virus (ZIKV) can be sexually transmitted and replicative particles were first detected in a semen sample from a patient during the 2013-14 French Polynesia outbreak. Here we describe the virus isolation from semen of a patient returning to Italy from Brazil.
Insights
Zika virus (ZIKV) is sexually transmissible, confirmed by isolation from a patient's semen returning from Brazil. This finding reinforces understanding of ZIKV sexual transmission routes.
Area of Science:
- Virology
- Infectious Diseases
- Public Health
Background:
- Zika virus (ZIKV) outbreaks have highlighted its potential for sexual transmission.
- Previous detection of ZIKV in semen occurred during the 2013-14 French Polynesia outbreak.
Observation:
- A patient returning to Italy from Brazil was diagnosed with ZIKV infection.
- Semen samples were collected and analyzed from the infected patient.
Findings:
- Replicative Zika virus particles were successfully isolated from the patient's semen.
- This case provides further evidence of ZIKV shedding in semen.
Implications:
- Confirms sexual transmission as a significant route for ZIKV.
- Informs public health strategies for ZIKV prevention and control.
- Highlights the importance of considering sexual contact in ZIKV transmission dynamics.
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