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Updated: Mar 2, 2026

Isolation and Quantification of Zika Virus from Multiple Organs in a Mouse

Isolation and Quantification of Zika Virus from Multiple Organs in a Mouse

Published on: August 15, 2019

Zika virus isolation from semen.

Elena Percivalle¹, Maurizio Zavattoni¹, Fausto Fausto^1,2

¹Microbiology and Virology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

The New Microbiologica

|May 18, 2017

Summary

Zika virus (ZIKV) is sexually transmissible, confirmed by isolation from a patient's semen returning from Brazil. This finding reinforces understanding of ZIKV sexual transmission routes.

Keywords:

Semen Viral isolation Zika virus

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Last Updated: Mar 2, 2026

Isolation and Quantification of Zika Virus from Multiple Organs in a Mouse

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Evaluation of Zika Virus-specific T-cell Responses in Immunoprivileged Organs of Infected Ifnar1-/- Mice

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Published on: April 26, 2018

Area of Science:

Virology
Infectious Diseases
Public Health

Background:

Zika virus (ZIKV) outbreaks have highlighted its potential for sexual transmission.
Previous detection of ZIKV in semen occurred during the 2013-14 French Polynesia outbreak.

Observation:

A patient returning to Italy from Brazil was diagnosed with ZIKV infection.
Semen samples were collected and analyzed from the infected patient.

Findings:

Replicative Zika virus particles were successfully isolated from the patient's semen.
This case provides further evidence of ZIKV shedding in semen.

Implications:

Confirms sexual transmission as a significant route for ZIKV.
Informs public health strategies for ZIKV prevention and control.
Highlights the importance of considering sexual contact in ZIKV transmission dynamics.