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Itraconazole activity against fungal germination
V Strippoli1, N Simonetti, A Retico
1Institute of Microbiology, University of Rome La Sapienza, Italy.
Abstract:
Itraconazole was found to be superior to ketoconazole in its antifungal activity in vitro against Hyphomycetes and Candida. In particular, complete inhibition of germination of Candida albicans and Aspergillus spp. by a lower dose of itraconazole can explain the better activity in vivo of this drug.