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Published on: February 23, 2014
[Acute otitis media in the children: etiology and the problems of antibacterial therapy]
I N Protasova1, O V Per'yanova1, T S Podgrushnaya2
1V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Russian Ministry of Health, Krasnoyarsk, Russia, 660022; Russian-Japanese Centre of Microbiology, Metagenomics and Infectious Diseases of V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Russian Ministry of Health, Krasnoyarsk, Russia, 660022.
Insights
This review examines acute otitis media causes in children, the role of biofilms, and antibiotic effectiveness. It also provides practical prevention guidelines for acute otitis media.
Area of Science:
- Pediatrics
- Infectious Diseases
- Microbiology
Background:
- Acute otitis media (AOM) is a common childhood infection.
- Biofilms play a significant role in the development and persistence of AOM.
- Understanding causative agents and their antibiotic sensitivities is crucial for effective treatment.
Purpose of the Study:
- To review current literature on the etiology of AOM in children.
- To elucidate the role of biofilms in AOM pathogenesis.
- To assess the antibiotic susceptibility of key AOM pathogens and develop prevention strategies.
Main Methods:
- Comprehensive literature search of available studies on AOM etiology, biofilms, and antibiotic sensitivity.
- Analysis of data on common causative microorganisms and their resistance patterns.
- Synthesis of findings to formulate evidence-based prevention guidelines.
Main Results:
- Identified primary etiological agents of AOM in pediatric populations.
- Highlighted the significant contribution of bacterial biofilms to recurrent and chronic AOM.
- Documented varying sensitivities of causative pathogens to different antibiotic classes.
Conclusions:
- Effective management of AOM requires understanding its complex etiology and the impact of biofilms.
- Antibiotic stewardship is essential, considering pathogen resistance patterns.
- Evidence-based guidelines are proposed for the prevention of AOM in children.
Abstract:
The objective of the present review was to summarize the currently available literature data on etiology of acute otitis media in the children, the role of biofilms in the development of this pathology, and sensitivity of its principal causative factors to various antibiotic medications. The secondary objective was to elaborate the practical guidelines for the prevention of acute otitis media in the children.
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