Related Experiment Video
Updated: Mar 2, 2026

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders
Published on: November 1, 2024
[Emotional impairments and their correction in patients with migraine]
L S Chutko1, S Yu Surushkina1, E A Yakovenko1
1N.P. Bekhtereva Institute of Human Brain, Russian Academy of Sciences, Saint Petersburg, Russia.
Aim:
To study emotional impairments in patients with migraine and to evaluate the efficiency of Noophen therapy for this pathology.
Subjects And Methods:
63 patients aged 18 to 45 years with migraine without aura were examined. 56 patients used prophylactic antimigraine therapy: Group 1 (n = 26) received metoprolol and Group 2 took metoprolol in combination with Noophen.
Results:
The patients with migraine had a significantly higher level of alexithymia than the controls. Concomitant anxiety disorders were found in 47 (74.6%) cases. The study provided evidence that the treatment was highly effective in Group 2 that exhibited a more pronounced decrease in pain intensity, a greater reduction in the levels of anxiety, and more vital activity.
Conclusion:
The results of this study allow a conclusion that emotional impairments are implicated in the pathogenesis and clinical presentations of migraine and that it is appropriate to use Noophen for the treatment of this pathology.

