Related Experiment Video
Updated: Mar 2, 2026

Visualizing Lymph Node Structure and Cellular Localization using Ex-Vivo Confocal Microscopy
Published on: August 9, 2019
[The age changes of lymphoid organs structure: review of literature]
I V Maiborodin1, M K Agzaev1, T M Ragimova1
1Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the RAS, Novosibirsk, 630090, Russian Federation; imai@mail.ru.
Abstract:
Numerous and often contradictory research results specify that the mechanism of increased susceptibility to diseases in old age has no satisfactory explanation so far. Together with it in literature almost completely there are no comparative data on features of surgery and injury influence on a structure and functions of lymphoid organs at patients of different age groups. However, lymph nodes are a marker of activity of inflammatory process in the region, on their changes it is possible to estimate precisely productivity of different medical actions, to predict development of many complications, and, thus, successfully to take actions for their prophylaxis. All this is especially important and actual because of constant increase in average age, in life expectancy of human population and strengthening of surgical activity at patients of advanced and old age.
More Related Videos
07:58Quantitative Imaging of Lineage-specific Toll-like Receptor-mediated Signaling in Monocytes and Dendritic Cells from Small Samples of Human Blood
Published on: April 16, 2012
09:10Generation of Lymph Node-fat Pad Chimeras for the Study of Lymph Node Stromal Cell Origin
Published on: December 16, 2013
Related Concept Videos
Lymphoid Cells and Tissues
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Primary Lymphoid Organs
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
Secondary Lymphoid Organs
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
Detailed Structure and Function of Lymph Nodes
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
Functions of the Lymphatic and Immune System
The primary lymphoid organs, including the bone marrow and the thymus, serve as the maturation sites for lymphocytes. Secondary lymphoid organs, like the mucosa-associated lymphoid tissue, activate these lymphocytes and serve as...
The Effect of Aging on Tissues