Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Kidney Transplant I: Introduction

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

International Society for Heart and Lung Transplantation Scientific Statement on pulmonary antibody-mediated rejection and proposed graft, antibody, and pathology (GAP) definition.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026

Same author

A single-center experience of 2000 adult lung transplants.

The Journal of thoracic and cardiovascular surgery·2026

Same author

Trends in primary graft dysfunction and early mortality following lung transplantation: A single center experience.

JHLT open·2026

Same author

Venous Thromboembolism in Brain-Dead Organ Donors: A Prospective Study of Prevalence, Management, and Impact on Organ Utilization and Recipient Outcomes.

Clinical transplantation·2025

Same author

The NHLBI lung transplant consortium 2025 steering committee report: Strategies to maximize the use of the consortium for advancing lung transplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2025

Same author

Atg16l1 promotes lung transplant tolerance by regulating glycolysis in macrophages.

bioRxiv : the preprint server for biology·2025

Same journal

Clinical Relevance of Donor-Specific IgM Antibodies in HLA Incompatible Renal Transplantation: A Retrospective Single-Center Study.

Clinical transplants·2017

Same journal

Influenza Immunization and the Generation of Anti-HLA and Anti-MICA Antibodies in Patients with Renal Failure and in Kidney Transplant Recipients.

Clinical transplants·2017

Same journal

From Accurate Assessment of Anti-HLA Antibody MFI to Complement-Binding Assays.

Clinical transplants·2017

Same journal

Post-transplant Desensitization for Deceased Donor Kidney Transplant Recipients: A Single Center Experience.

Clinical transplants·2017

Same journal

Acute Rejection in 6-Antigen HLA-Matched Kidney Transplant Recipients: Risk Factors and Outcomes from the Wisconsin Allograft Recipient Database (WisARD).

Clinical transplants·2017

Same journal

C1q Donor-Specific Antibody Associates with Post-transplant Biopsy Findings in Highly- Sensitized Kidney Transplant Recipients.

Clinical transplants·2017

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 2, 2026

Orthotopic Left Lung Transplantation in Rats

Orthotopic Left Lung Transplantation in Rats

Published on: July 3, 2025

Advancing Lung Transplantation.

Ramsey R Hachem¹

¹Washington University School of Medicine, Division of Pulmonary and Critical Care, St. Louis, MO.

Clinical Transplants

|May 18, 2017

Summary

This summary is machine-generated.

Lung transplantation is a common therapy for lung disease, but chronic rejection limits long-term survival. New strategies are needed to prevent and treat this rejection to improve patient outcomes.

Keywords:

chronic rejection graft survival lung transplantation

More Related Videos

Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP

Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP

Published on: February 14, 2022

Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation

Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation

Published on: November 10, 2023

Related Experiment Videos

Last Updated: Mar 2, 2026

Orthotopic Left Lung Transplantation in Rats

Orthotopic Left Lung Transplantation in Rats

Published on: July 3, 2025

Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP

Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP

Published on: February 14, 2022

Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation

Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation

Published on: November 10, 2023

Area of Science:

Cardiology and Thoracic Surgery
Immunology

Background:

Lung transplantation has become a standard treatment for end-stage lung disease, with ~4,000 procedures annually worldwide.
Organ donor shortage and disappointing long-term survival (median ~6 years) remain significant challenges.
Chronic rejection is the primary cause of graft failure and mortality beyond the first year post-transplant.

Purpose of the Study:

To highlight the critical need for novel interventions to combat chronic rejection after lung transplantation.
To emphasize the importance of multi-center randomized controlled trials for evaluating new treatment strategies.

Main Methods:

This abstract does not detail specific methods but emphasizes the need for clinical trials.

Main Results:

This abstract does not present specific results but outlines the problem of chronic rejection.
Chronic rejection leads to allograft failure and patient death, necessitating new therapeutic approaches.

Conclusions:

There is an urgent need for strategies to prevent and treat chronic rejection in lung transplant recipients.
Further research and clinical trials are essential to improve long-term outcomes in lung transplantation.