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Understanding Spontaneous Conversion: The Case of the Ly6C- Monocyte
Sara Polletti1, Gioacchino Natoli2
1Humanitas Clinical and Research Center, Via Manzoni 56, 20089 Rozzano, Milan, Italy; Humanitas University, School of Medicine, Department of Biomedical Sciences, Via Manzoni 113, 20089 Rozzano, Milan, Italy.
Immunity
|May 18, 2017
Abstract:
Mouse blood monocytes include two main subsets usually discriminated by the expression of the Ly6C surface marker. The study by Mildner et al. (2017) in this issue of Immunity clarifies the transcriptional circuits controlling the generation of Ly6C- cells from their obligate precursors, the Ly6C+ monocytes.

