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Endoscopic Management of Pancreatic Fluid Collections in Children
Zaheer Nabi1, Rupjyoti Talukdar1, D Nageshwar Reddy1
1Asian Institute of Gastroenterology, Hyderabad, India.
Insights
Acute pancreatitis in children is rising. Endoscopic ultrasound-guided drainage is a promising, safe, and effective treatment for pancreatic fluid collections in pediatric patients, though more research is needed.
Area of Science:
- Pediatric Gastroenterology
- Interventional Endoscopy
Background:
- Acute pancreatitis incidence in children is increasing.
- Pancreatic fluid collections are common complications of severe acute pancreatitis in pediatric patients.
- The natural history and optimal management of these collections in children remain poorly understood.
Purpose of the Study:
- To review the current understanding of pancreatic fluid collection management in children.
- To evaluate the safety and efficacy of endoscopic ultrasound (EUS)-guided drainage for pediatric pancreatic fluid collections.
- To discuss the role of different endoprostheses in managing these collections.
Main Methods:
- Review of existing literature on EUS-guided drainage of pancreatic fluid collections in pediatric populations.
- Comparison with established outcomes in adult patients.
- Discussion of endoprosthesis types, including plastic and metal stents.
Main Results:
- Endoscopic management, particularly EUS-guided drainage, shows promise for pediatric pancreatic fluid collections.
- While data in children is limited to small case series, results in adults are excellent.
- Metal stents, especially fully covered ones, offer advantages over plastic stents due to wider lumens and less clogging.
Conclusions:
- EUS-guided drainage is a safe and effective endoscopic approach for pediatric pancreatic fluid collections.
- Further prospective studies with larger sample sizes are necessary to confirm these findings and establish definitive guidelines for the pediatric age group.
Abstract:
The incidence of acute pancreatitis in children has increased over the last few decades. The development of pancreatic fluid collection is not uncommon after severe acute pancreatitis, although its natural course in children and adolescents is poorly understood. Asymptomatic fluid collections can be safely observed without any intervention. However, the presence of clinically significant symptoms warrants the drainage of these fluid collections. Endoscopic management of pancreatic fluid collection is safe and effective in adults. The use of endoscopic ultrasound (EUS)-guided procedure has improved the efficacy and safety of drainage of pancreatic fluid collections, which have not been well studied in pediatric populations, barring a scant volume of small case series. Excellent results of EUS-guided drainage in adult patients also need to be verified in children and adolescents. Endoprostheses used to drain pancreatic fluid collections include plastic and metal stents. Metal stents have wider lumens and become clogged less often than plastic stents. Fully covered metal stents specifically designed for pancreatic fluid collection are available, and initial studies have shown encouraging results in adult patients. The future of endoscopic management of pancreatic fluid collection in children appears promising. Prospective studies with larger sample sizes are required to establish their definitive role in the pediatric age group.
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