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Published on: October 21, 2022
Corneal biomechanical properties in healthy children measured by corneal visualization scheimpflug technology
1Zhongshan Ophthalmic Center and State Key Laboratory of Ophthalmology, Sun Yat-sen University, 54S Xianlie Road, 510060, Guangzhou, China.
Insights
This study found healthy children
Area of Science:
- Ophthalmology
- Biomechanical Engineering
- Pediatric Eye Care
Background:
- Corneal biomechanical properties are crucial for ocular health.
- Understanding these properties in children is essential for early detection of eye conditions.
- Corneal Visualization Scheimpflug Technology (CST) offers advanced assessment capabilities.
Purpose of the Study:
- To evaluate corneal biomechanical properties in healthy Chinese children.
- To assess the interocular symmetry of these properties.
- To investigate the influence of demographic factors, central corneal thickness (CCT), and intraocular pressure (IOP) on corneal biomechanics.
Main Methods:
- Bi-ocular examinations were performed on 108 healthy children (ages 4-18).
- Corneal Visualization Scheimpflug Technology (CST) measured various biomechanical parameters.
- Pearson correlation analysis examined the impact of CCT, spherical equivalent (SE), and IOP on CST measurements.
Main Results:
- High interocular symmetry was observed in SE, IOP, and CCT.
- Most CST biomechanical parameters showed remarkable symmetry between eyes, with minor exceptions (A2L, A1DA).
- Corneal biomechanical parameters were significantly correlated with CCT and IOP, but minimally influenced by age, SE, or sex.
Conclusions:
- Healthy children's eyes exhibit interocular symmetry in corneal biomechanics.
- CCT and IOP are significant modulators of corneal biomechanical parameters in pediatric populations.
- CST is a valuable tool for assessing corneal biomechanics in children.
Background:
The aim of this study was to evaluate corneal biomechanical properties in a population of healthy children in China using corneal visualization Scheimpflug technology (CST).
Methods:
All children underwent complete bi-ocular examinations. CST provided intraocular pressure (IOP) and corneal biomechanical parameters, including time, velocity, length and deformation amplitude at first applanation (A1T, A1V, A1L, A1DA), at second applanation (A2T, A2V, A2L, A2DA), highest concavity time (HCT), maximum deformation amplitude (MDA), peak distance (PD), and radius of curvature (RoC). Pearson correlation analysis was used to assess the impacts of demographic factors, central corneal thickness (CCT), spherical equivalent (SE), and IOP on corneal biomechanics.
Results:
One hundred eight subjects (32 girls and 76 boys) with the mean age of 10.80 ± 4.13 years (range 4 to18 years) were included in the final analyses. The right and left eyes were highly symmetrical in SE (p = 0.082), IOP (p = 0.235), or CCT (p = 0.210). Mean A1T of the right eyes was 7.424 ± 0.340 ms; the left eyes 7.451 ± 0.365 ms. MDA was 0.993 ± 0.102 mm in the right eyes and 0.982 ± 0.100 mm in the left eyes. Mean HCT of the right eyes was 16.675 ± 0.502 ms; the left eyes 16.735 ± 0.555 ms. All CST parameters of both eye were remarkably symmetrical with the exception of A2L (p = 0.006), A1DA (p = 0.025). The majority of CST parameters of both eyes were significantly correlated with CCT and IOP (p < 0.05). However, age, SE, and sex exert little influence on the CST measurements.
Conclusions:
This study found interocular symmetry in corneal biomechanics in healthy children eyes. Several CST biomechanical parameters in children are modified by CCT and IOP.
