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Late-onset adrenal hyperplasia in north Indian hirsute women
A Mithal1, A C Ammini, M M Godbole
1Department of Endocrinology and Metabolism, All-India Institute of Medical Sciences, New Delhi.
Hormone Research
|January 1, 1988
Abstract:
The occurrence of late-onset congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency was studied in 60 consecutive hirsute women by means of adrenocorticotrophin (ACTH)-stimulated serum 17-hydroxyprogesterone (17-OHP) levels. Five (8.3%) women had an exaggerated response (ACTH-stimulated 17-OHP 3,160 +/- 560 ng/dl). All of them had regular periods and 3 were virilized. The other 2 were indistinguishable from those with idiopathic hirsutism or polycystic ovarian disease.