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Hydrocortisone resolves persistent neonatal jaundice in multiple hormone deficiencies.

R Steinherz¹, A Rachmel, Z Josephsberg

¹Department of Pediatrics A, Beilinson Medical Center, Petah Tiqva, Israel.

Helvetica Paediatrica Acta

|November 1, 1988

Summary

Congenital hypothalamo-pituitary derangement can cause prolonged neonatal cholestasis, hypoglycemia, and a small penis. Hydrocortisone therapy effectively treated jaundice, unlike thyroxine replacement.

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Area of Science:

Pediatric Endocrinology
Neonatalogy
Endocrinology

Background:

Prolonged neonatal cholestasis is a significant clinical challenge.
Congenital hypothalamo-pituitary derangement can manifest with diverse endocrine abnormalities.
Association of neonatal cholestasis with specific endocrine deficiencies requires further elucidation.

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