Contrast use in relation to the arterial access site for percutaneous coronary intervention: A comprehensive

Rahman Shah1, Anthony Mattox1, M Rehan Khan1

  • 1Rahman Shah, Anthony Mattox, Section of Cardiovascular Medicine, School of Medicine, University of Tennessee, Memphis, TN 38104, United States.

Insights

This meta-analysis found no significant difference in contrast volume used for percutaneous coronary intervention (PCI) via trans-radial access (TRA) versus trans-femoral access (TFA). Both methods are comparable in terms of contrast utilization.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Medical Imaging

Background:

  • Percutaneous coronary intervention (PCI) is a common procedure for treating coronary artery disease.
  • Trans-radial access (TRA) and trans-femoral access (TFA) are two primary vascular access routes for PCI.
  • The volume of contrast media used can impact patient outcomes and procedure costs.

Purpose of the Study:

  • To compare the amount of contrast media utilized during PCI procedures performed via trans-radial access (TRA) versus trans-femoral access (TFA).

Main Methods:

  • A systematic literature search was conducted across scientific databases and websites.
  • Randomized controlled trials (RCTs) comparing contrast volume in TRA versus TFA for PCI were included.
  • Data were extracted by two independent reviewers, and a meta-analysis was performed using a random-effects model to calculate the weighted mean difference (WMD) with 95% confidence intervals (CI).

Main Results:

  • The meta-analysis included 13 RCTs encompassing 3165 patients.
  • No statistically significant difference was observed in the amount of contrast media used between the TRA and TFA groups (WMD = -0.65 mL, 95% CI: -10.94-9.46 mL, P = 0.901).

Conclusions:

  • In patients undergoing PCI, the volume of contrast media used is not significantly different between trans-radial access and trans-femoral access.
  • This finding suggests that contrast utilization is comparable regardless of the access site chosen for PCI.
Abstract

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