Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Determination of Crystal Structures01:29

Determination of Crystal Structures

12
In the late 1800s, the revelation that light extended beyond visible wavelengths led to the discovery of X-rays by Wilhelm Roentgen. Recognized as high-energy electromagnetic radiation with short wavelengths, X-rays prompted exploration into their interaction with crystals. Max von Laue proposed in 1912 that the periodic arrangement of atoms, ions, or molecules in crystals would cause them to diffract X-rays, a hypothesis confirmed through experiments with copper sulfate and zinc sulfide...
12

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Utility of CT angiography in the comprehensive assessment of sinus of Valsalva aneurysms.

Clinical radiology·2026
Same author

[The effect of different coronary artery flow isolation techniques in off-pump coronary artery bypass grafting].

Zhonghua yi xue za zhi·2025
Same author

Retraction: Nanocomposite functionalized membranes based on silica nanoparticles cross-linked to electrospun nanofibrous support for arsenic(v) adsorption from contaminated underground water.

RSC advances·2025
Same author

[Comparison of the efficacy of anatomical resection versus hepatic parenchymal preservation preference in patients with solitary small hepatocellular carcinoma and cirrhosis: a multicenter retrospective study].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology·2025
Same author

Cross-Sectional and Longitudinal Patterns of Atrophy in Thalamic and Deep Gray Matter Nuclei in Frontotemporal Dementia.

medRxiv : the preprint server for health sciences·2025
Same author

[A case report of Roux-en-Y gastric bypass combined with radical gastrectomy for severe obesity complicated with gastric cancer].

Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery·2024

Related Experiment Video

Updated: Mar 2, 2026

Retrospective Cardiac Gating with A Prototype Small-Animal X-ray Computed Tomograph
05:32

Retrospective Cardiac Gating with A Prototype Small-Animal X-ray Computed Tomograph

Published on: February 21, 2025

757

Hybrid Pixel-Waveform (HPWF) Enabled CdTe Detectors for Small Animal Gamma-Ray Imaging Applications.

A Groll1, K Kim2, H Bhatia3

  • 1Nuclear, Plasma, and Radiological Engineering, University of Illinois at Urbana-Champaign, IL 61801 USA (primary: groll1@illinois.edu).

IEEE Transactions on Radiation and Plasma Medical Sciences
|May 19, 2017
PubMed
Summary

This study introduces small-pixel cadmium telluride (CdTe) gamma ray detectors with a hybrid pixel-waveform (HPWF) readout system. These detectors offer high-resolution imaging for applications like small animal PET and SPECT.

More Related Videos

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera
06:28

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Published on: January 30, 2020

13.3K
Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
12:24

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers

Published on: July 17, 2012

12.9K

Related Experiment Videos

Last Updated: Mar 2, 2026

Retrospective Cardiac Gating with A Prototype Small-Animal X-ray Computed Tomograph
05:32

Retrospective Cardiac Gating with A Prototype Small-Animal X-ray Computed Tomograph

Published on: February 21, 2025

757
Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera
06:28

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Published on: January 30, 2020

13.3K
Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
12:24

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers

Published on: July 17, 2012

12.9K

Area of Science:

  • Medical Imaging
  • Semiconductor Detectors
  • Gamma Ray Detection

Background:

  • Traditional gamma ray detectors face limitations in achieving high spatial and timing resolution.
  • Cadmium telluride (CdTe) and cadmium zinc telluride (CZT) are promising materials for radiation detection due to their high atomic number and room-temperature operation.
  • Advancements in readout electronics are crucial for enhancing detector performance.

Purpose of the Study:

  • To design and evaluate a novel hybrid pixel-waveform (HPWF) readout system for small-pixel CdTe gamma ray detectors.
  • To assess the performance of these detectors for gamma ray imaging applications, including small animal PET and SPECT.
  • To investigate the potential of HPWF readout for achieving high energy, timing, and spatial resolution, along with depth-of-interaction (DOI) information.

Main Methods:

  • Development of prototype HPWF-CdTe detectors featuring small anode pixels (350 μm) and a custom CMOS pixel-ASIC.
  • Integration of a discrete waveform sampling circuitry to digitize the cathode signal waveform.
  • Experimental evaluation of intrinsic timing, energy, and spatial resolution, and DOI partitioning methods.

Main Results:

  • The HPWF readout system successfully provided pixel address, energy, timing, and DOI information.
  • Experimental evaluation demonstrated the potential for high-resolution imaging capabilities.
  • The developed detectors showed promising performance for gamma ray imaging applications.

Conclusions:

  • The HPWF readout system is a viable technology for small-pixel CdTe gamma ray detectors.
  • These detectors show significant potential for ultrahigh-resolution imaging in modalities like small animal PET and SPECT.
  • Further development could lead to improved performance and broader applications in nuclear medicine and other fields.