Related Experiment Video
Updated: Mar 2, 2026

Cerenkov Luminescence Imaging CLI for Cancer Therapy Monitoring
Published on: November 13, 2012
Sci-Fri PM: Delivery - 10: Megavoltage x-ray imaging detector based on cerenkov effect
A Teymurazyan1, G Pang1,2,3,4
1Imaging Research, Sunnybrook Health Science Centre and Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
Abstract:
A Monte Carlo simulation was used to study imaging and dosimetric characteristics of a novel design of a megavoltage (MV) x-ray imaging detector. The proposed detector consists of a matrix of optical fibers aligned with the incident x-rays and coupled to an active matrix flat-panel imager (AMFPI) for image readout. The new design relies on Cerenkov effect for MV x-ray imaging and is named CPID (for Cerenkov Portal Imaging Device). When MV x-rays are incident on CPID, they interact within the volume of the detector primarily via Compton effect and pair-production, resulting in electrons and positrons. From these charged particles, those with sufficient energy, trigger production of optical light via Cerenkov effect. The light that is generated in the optical fibre cores within the acceptance angle of the fibers is guided towards the AMFPI. Properties, such as detection efficiency, modulation transfer function, zero frequency detective quantum efficiency (DQE), and energy response of the detector, have been investigated. It has been shown that the proposed detector can have a zero-frequency DQE more than an order of magnitude higher than that of current electronic portal imaging device (EPID) systems and yet a spatial resolution comparable to that of video-based EPIDs. In additional the proposed detector is less sensitive to scattered x-rays than current EPIDs.
Related Concept Videos
Determination of Crystal Structures
X-ray Imaging
Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
Photoelectric Effect
Radiological Investigation I: X-ray and CT
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...

