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SU-E-T-292: New Technique for Developing Proton Range Compensator Using Three-Dimensional Printer.

S Ju1,2,3, M Kim1,2,3, C Hong1,2,3

  • 1Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Medical Physics
|May 19, 2017
PubMed
Summary
This summary is machine-generated.

A new 3D-printed proton range compensator (PRC-3DP) demonstrates comparable physical accuracy and dosimetrical characteristics to conventional machined PRCs (PRC-CMM). This 3D printing method offers significant system minimization for proton therapy applications.

Keywords:
BrainCancerCollisional energy lossComputer softwareDosimetryManufacturingMillingProtonsSemiconductor device fabricationUltraviolet light

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Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Biomedical Engineering

Background:

  • Proton range compensators (PRCs) are crucial for precise dose delivery in proton therapy.
  • Conventional PRC manufacturing using computerized milling machines (CMM) can be time-consuming and costly.
  • Advancements in additive manufacturing, such as 3D printing (3DP), offer potential for more efficient and customizable medical device production.

Purpose of the Study:

  • To develop and evaluate a novel 3D-printed proton range compensator (PRC-3DP).
  • To compare the physical accuracy and dosimetrical characteristics of PRC-3DP with conventionally manufactured PRCs (PRC-CMM).
  • To assess the feasibility of 3DP for producing patient-specific compensators in proton therapy.

Main Methods:

  • A PRC for brain cancer treatment was designed using treatment planning system (TPS) data.
  • The PRC-3DP was fabricated using a 3D printer with UV curable acrylic plastic.
  • Physical dimensions (thickness) and dosimetrical characteristics (SPR, SOBP, DFO, FWHM) were measured and compared against TPS data and PRC-CMM.
  • PRC-CMM was manufactured using a computerized milling machine (CMM) from PMMA.

Main Results:

  • No significant difference in physical thickness was observed between PRC-3DP and PRC-CMM compared to calculated values.
  • Both PRC types exhibited similar stopping power ratios (SPR) compared to water.
  • Dosimetrical evaluations showed comparable results for Spread-Out Bragg Peak (SOBP), Distal Fall-Off (DFO), and Full Width at Half Maximum (FWHM) between PRC-3DP, PRC-CMM, and TPS data.
  • No significant dosimetrical differences were found between the 3D-printed and milled PRCs.

Conclusions:

  • 3D-printed proton range compensators (PRC-3DP) exhibit comparable physical accuracy and dosimetrical performance to conventional machined compensators (PRC-CMM).
  • 3DP offers a viable alternative manufacturing method for PRCs, potentially leading to system minimization and improved efficiency in proton therapy.
  • The developed 3DP system holds promise for creating customized compensators for radiation therapy applications.