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SU-E-T-209: Four-Dimensional Gamma Method for Dose-Guided Radiotherapy.

Y Wang¹, G Li¹, Q Ren¹

¹Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei, Anhui.

Medical Physics

|May 19, 2017

Summary

The improved four-dimensional (4D) Gamma Method enhances real-time dose verification in radiotherapy by reducing systematic errors. This advancement allows for more accurate treatment delivery and assessment of accelerator stability.

Keywords:

Dosimetry Error analysis Ionization chambers Radiation therapy

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Area of Science:

Medical Physics
Radiotherapy
Radiation Oncology

Background:

The traditional Gamma Evaluation Method is effective for dose distribution comparison but lacks accuracy in real-time verification due to unstable systematic factors.
Dose-guided Radiotherapy (DGRT) requires precise real-time dose verification to ensure treatment accuracy.

Purpose of the Study:

To improve the Gamma Method formula to reduce systematic errors.
To develop a four-dimensional (4D) Gamma Method for accurate real-time dose verification in DGRT.

Main Methods:

The gamma index formula was modified to include time as a variable, proportional to monitor units (MU), alongside dose and distance.
An algorithm was developed using Microsoft Visual C++ 6.0.
The improved method was validated using two radiotherapy treatment plans (Conformal and Intensity-Modulated) and dose measurements from a 2D ionization chamber (MatriXX).

Main Results:

The original Gamma Method showed errors attributed to systematic factors.
The improved 4D Gamma Method significantly reduced errors from systematic factors, meeting DGRT requirements for real-time verification.
The method demonstrated its utility in evaluating the stability of radiation therapy accelerators.

Conclusions:

The 4-dimensional Gamma Method effectively reduces systematic errors in dose verification.
This method can be utilized to assess the stability of different accelerators, enhancing quality assurance in radiotherapy.