SU-E-J-31: Direct Point Dose Verification Using IGRT for Actual Beam Delivery.
K Matsubara1,2,3, R Kohno1,2,3, S Nishioka1,2,3
1Graduate School of Human Health Sciences, Tokyo Metropolitan University.
Medical Physics
|May 19, 2017
Summary
Image-guided radiation therapy (IGRT) precisely measures delivered radiation dose in head-and-neck cancer patients. This study confirms IGRT
Area of Science:
- Medical Physics
- Radiation Oncology
- Dosimetry
Background:
- Radiation therapy planning relies on initial CT scans, but patient anatomical changes (tumor shrinkage, weight loss) and daily positioning errors can lead to inaccurate delivered doses.
- Accurate assessment of the actual delivered radiation dose is crucial for evaluating the clinical and dosimetric consequences in head-and-neck cancer patients undergoing radiation therapy.
Purpose of the Study:
- To experimentally evaluate the usefulness of Image-Guided Radiation Therapy (IGRT) procedures for accurate irradiations.
- To determine the actual delivered dose for a head-and-neck site using direct point dose measurements with metal-oxide-semiconductor field-effect transistor (MOSFET) detectors.
Main Methods:
- An anthropomorphic phantom simulating a head-and-neck site was used for treatment planning and beam delivery experiments.
- MOSFET detectors were placed inside the phantom, which was immobilized and scanned using simulation-CT.
- Positioning was verified using mega-voltage cone-beam CT (MVCBCT) before irradiation, and measured doses were compared with calculated doses.
Main Results:
- IGRT, specifically MVCBCT, enabled precise patient positioning within 1 mm in all directions.
- Measured doses from MOSFET detectors closely matched calculated doses, with agreement within ±3%, even in high dose gradient regions.
Conclusions:
- The study experimentally validated the actual delivered dose for a head-and-neck site using MOSFET detectors.
- The findings confirm that IGRT procedures are effective in ensuring accurate radiation delivery.
Keywords:
CancerComputed tomographyDosimetryDrug deliveryImage guided radiation therapyMOSFETsMedical imagingMedical treatment planningRadiation therapyRadiation treatment

