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SU-E-J-02: Accuracy of Fiducial Marker Localization Using Axial and Helical CT, Cone-Beam CT and KV Imaging
Medical Physics
|May 19, 2017
Summary
Image slice thickness and motion significantly impact fiducial marker accuracy in CT imaging. kV imaging offers superior precision for accurate tumor localization in image-guided radiation therapy.
Area of Science:
- Medical Imaging Physics
- Radiation Oncology
Background:
- Accurate localization of implanted fiducial markers is critical for image-guided radiation therapy (IGRT).
- CT imaging parameters, including slice thickness and motion, can introduce localization errors.
Purpose of the Study:
- To evaluate localization errors of fiducial markers using various CT imaging modalities.
- To assess the impact of slice thickness and motion on marker accuracy in axial (ACT), helical CT (HCT), cone beam CT (CBCT), and kV imaging.
Main Methods:
- A thorax phantom with fiducial markers of varying sizes (2.5-20mm) was imaged using ACT, HCT, CBCT, and kV imaging.
- Scans were performed with and without simulated motion (15mm amplitude, 15 cycles/min).
- CT images were reconstructed at different slice thicknesses (0.625-5mm), and marker location and length were measured.
Main Results:
- Increased slice thickness enlarged apparent marker size and displaced marker centers in ACT and HCT.
- Phantom motion further increased marker size and center displacement, with HCT showing more prominent shifts.
- kV imaging provided the sharpest marker images with minimal size discrepancies compared to actual marker dimensions.
Conclusions:
- Slice thickness and motion introduce significant fiducial marker localization errors in ACT and HCT.
- These distortions necessitate careful consideration in CT-based IGRT for precise tumor localization and patient positioning.
- kV imaging demonstrates superior accuracy for fiducial marker visualization in IGRT applications.

