Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of Neisseria cinerea with ocular infections in paediatric patients.

The Journal of infection·1998
Same author

Transcription from the thyroid hormone-dependent promoter of the Xenopus laevis thyroid hormone receptor betaA gene requires a novel upstream element and the initiator, but not a TATA Box.

The Journal of biological chemistry·1998
Same author

Unique organization and involvement of GAGA factors in transcriptional regulation of the Xenopus stromelysin-3 gene.

Nucleic acids research·1998
Same author

Inhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70.

Genes & development·1998
Same author

The value of neck drain in esophageal surgery: a randomized trial.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·1998
Same author

Unusual features of the Drosophila melanogaster telomere transposable element HeT-A are conserved in Drosophila yakuba telomere elements.

Proceedings of the National Academy of Sciences of the United States of America·1998

Related Experiment Video

Updated: Mar 2, 2026

Author Spotlight: Improving Radiation Therapy Access with Radiation Planning Assistant
05:18

Author Spotlight: Improving Radiation Therapy Access with Radiation Planning Assistant

Published on: October 6, 2023

2.0K

SU-E-T-200: IMRT Patient Specific QA for On-Line Adaptive Radiotherapy.

Z Gao1, J Wong1, S Merrick1

  • 1Morristown Memorial Hospital, Morristown, NJ.

Medical Physics
|May 19, 2017
PubMed
Summary
This summary is machine-generated.

This study presents an alternative method for quality assurance in online adaptive radiotherapy. A second treatment planning system (TPS) can verify intensity-modulated radiation therapy (IMRT) fluences, serving as a valuable patient-specific QA when direct measurements are not feasible.

Keywords:
AnatomyCancerComputed tomographyDosimetryIntensity modulated radiation therapyQuality assuranceRadiation therapyRadiation treatment

More Related Videos

Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System
08:25

Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System

Published on: April 11, 2018

16.1K
Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

16.3K

Related Experiment Videos

Last Updated: Mar 2, 2026

Author Spotlight: Improving Radiation Therapy Access with Radiation Planning Assistant
05:18

Author Spotlight: Improving Radiation Therapy Access with Radiation Planning Assistant

Published on: October 6, 2023

2.0K
Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System
08:25

Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System

Published on: April 11, 2018

16.1K
Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

16.3K

Area of Science:

  • Radiation Oncology
  • Medical Physics
  • Radiotherapy Technology

Background:

  • Online adaptive intensity-modulated radiation therapy (IMRT) demands extensive resources and rigorous quality assurance (QA).
  • Patient-specific QA, particularly fluence measurements, is challenging to perform in real-time before treatment delivery.
  • Current methods for verifying IMRT plans before treatment are often clinically unrealistic.

Purpose of the Study:

  • To develop and validate an alternative method for patient-specific QA in online adaptive IMRT.
  • To assess the feasibility of using a second treatment planning system (TPS) for fluence verification.
  • To evaluate the accuracy of point dose and fluence measurements against TPS calculations.

Main Methods:

  • 28 IMRT plans for prostate cancer patients were generated using Prowess Panther 5.1.
  • Fluence recalculations were performed using Pinnacle 9.2 on a flat surface phantom.
  • Fluence measurements were conducted using a Matrixx IMRT Device on a Siemens Artiste accelerator.

Main Results:

  • Point dose differences between Prowess and Pinnacle were within 1%.
  • Point dose differences between measurements and Prowess calculations were within 3%.
  • Fluence comparisons using gamma criteria (3%3mm) showed passing rates consistently above 98.5% between TPS and measurements.

Conclusions:

  • A second TPS can effectively verify planned IMRT fluences.
  • This method provides a valuable patient-specific QA alternative when conventional measurements are not feasible.
  • This approach enhances the efficiency and reliability of online adaptive radiotherapy QA.