Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cooling positronium to ultralow velocities with a chirped laser pulse train.

Nature·2024
Same author

Evaluation of epithelial and mesenchymal cell markers in canine urinary bladder transitional cell carcinoma.

Veterinary journal (London, England : 1997)·2020
Same author

A new SOBP-formation method by superposing specially shaped Bragg curves formed by a mini-ridge filter for spot scanning in proton beam therapy.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)·2019
Same author

Integrating quantitative morphological and intratumoural textural characteristics in FDG-PET for the prediction of prognosis in pharynx squamous cell carcinoma patients.

Clinical radiology·2018
Same author

Multiple Re-entry Closures After TEVAR for Ruptured Chronic Post-dissection Thoraco-abdominal Aortic Aneurysm.

EJVES short reports·2018
Same author

Association analysis of the ACTN3 R577X polymorphism with passive muscle stiffness and muscle strain injury.

Scandinavian journal of medicine & science in sports·2017

Related Experiment Video

Updated: Mar 2, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

21.2K

SU-E-T-506: Dosimetric Study for Shallow-Seated Tumor Using Passive/active Scanning Proton Beam.

C Toramatsu, T Matsuura, H Nihongi

    Medical Physics
    |May 19, 2017
    PubMed
    Summary
    This summary is machine-generated.

    A single spot scanning proton beam, with a custom pre-absorber, can effectively treat superficial lesions. This method offers good target coverage while sparing normal tissues, similar to multi-beam approaches.

    Keywords:
    CancerCobaltDosimetryMedical treatment planningProtonsSkinSurface treatments

    More Related Videos

    Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
    08:17

    Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

    Published on: June 7, 2015

    16.3K
    Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
    07:57

    Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

    Published on: March 24, 2022

    3.3K

    Related Experiment Videos

    Last Updated: Mar 2, 2026

    Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
    08:34

    Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

    Published on: February 6, 2019

    21.2K
    Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
    08:17

    Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

    Published on: June 7, 2015

    16.3K
    Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
    07:57

    Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

    Published on: March 24, 2022

    3.3K

    Area of Science:

    • Medical Physics
    • Radiation Oncology
    • Proton Therapy

    Background:

    • Superficial lesions pose treatment challenges in radiation oncology.
    • Spot scanning proton beam therapy offers precise dose delivery.
    • Optimizing beam configurations for superficial targets is crucial for minimizing dose to surrounding healthy tissues.

    Purpose of the Study:

    • To evaluate the feasibility of using a single spot scanning proton beam for treating superficial lesions.
    • To compare the efficacy and safety of a single spot scanning beam with a pre-absorber against conventional single and multi-beam techniques.

    Main Methods:

    • A cylindrical phantom with a simulated superficial target (0.5-4cm depth) was used.
    • Three treatment plans were generated: single uniform scanning beam, single spot scanning beam with pre-absorber, and a five-beam spot scanning plan.
    • Geant4 Monte Carlo simulations were employed to design the pre-absorber for the spot scanning beam.

    Main Results:

    • All plans achieved comparable target dose coverage (within 2.4%).
    • The single spot scanning beam with a pre-absorber demonstrated superior conformity (index 1.04) and a narrow lateral penumbra (0.73 cm), comparable to the uniform beam.
    • This approach also reduced skin dose and mean normal tissue dose compared to the multi-beam plan.

    Conclusions:

    • A single spot scanning proton beam, when combined with a properly designed pre-absorber, is a viable option for treating superficial lesions.
    • This technique provides excellent target coverage and effective normal tissue sparing.
    • It presents a promising alternative to more complex multi-beam configurations for superficial target treatments.