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WE-G-213CD-05: Beam's-Eye-View Prostate Motion Detection during Arc Radiotherapy
Y Yue1, P Nguyen1, J Rottmann1
1Brigham and Women's Hospital, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA.
Medical Physics
|May 19, 2017
Summary
A new algorithm accurately tracks prostate motion during arc radiotherapy, achieving millimeter-level precision. This method enhances treatment accuracy and patient safety in real-time during radiation therapy.
Area of Science:
- Radiation Oncology
- Medical Physics
- Image Guidance
Background:
- Prostate motion during radiotherapy can significantly impact treatment accuracy.
- Accurate tracking of prostate motion is crucial for effective arc radiotherapy delivery.
Purpose of the Study:
- To develop and validate a novel statistical algorithm for tracking prostate motion during clinical arc radiotherapy.
- To assess the algorithm's performance in both phantom and patient studies.
Main Methods:
- A dynamic phantom and clinical data from two prostate cancer patients undergoing volumetric modulated arc therapy (VMAT) were used.
- Fiducial markers implanted in the prostate were detected using a wavelet-based filter in beam's-eye-view (BEV) images.
- A statistical maximum a posteriori (MAP) algorithm estimated 3D prostate motion from 2D projections.
Main Results:
- The algorithm achieved a baseline accuracy of 0.69+/-0.56 mm in phantom studies.
- Intra-fraction prostate motion in patients ranged from 0.98+/-0.51 mm to 1.12+/-0.65 mm.
- The system demonstrated the capability to track motion with sub-millimeter accuracy.
Conclusions:
- Prostate motion during arc therapy can be tracked with high accuracy (within one millimeter).
- The developed technique is suitable for real-time, in-treatment room target tracking.
- This method can also be valuable for post-therapy evaluation of treatment accuracy.
