Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Accuracy and Precision

Accuracy and Precision

Scientists typically make repeated measurements of a quantity to ensure the quality of their findings and to evaluate both the precision and the accuracy of their results. Measurements are said to be precise if they yield very similar results when repeated in the same manner. A measurement is considered accurate if it yields a result that is very close to the true or the accepted value. Precise values agree with each other; accurate values agree with a true value. Highly accurate...

Improving Translational Accuracy

Improving Translational Accuracy

Improving Translational Accuracy

Improving Translational Accuracy

Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Olfactory vulnerability in older adults undergoing endoscopic skull base surgery: insights from olfactory strip elevation.

Rhinology·2026

Same author

Nasopharyngeal pneumococcal carriage in Indian children following 10-valent PCV (PNEUMOSIL®) introduction through India's universal immunization program: A post licensure cross-sectional study.

Vaccine·2025

Same author

Radiomics in non-oncologic musculoskeletal diseases: from pixels to practice.

Clinical radiology·2025

Same author

Interactions between descending and spinal circuits on motor output.

Experimental neurology·2025

Same author

Association between early job loss and prognosis among hepatocellular carcinoma survivors.

Occupational medicine (Oxford, England)·2025

Same author

The impact of employment stability on all-cause mortality among young workers.

Occupational medicine (Oxford, England)·2025

Search research articles

Related Experiment Video

Updated: Mar 2, 2026

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Published on: October 27, 2023

SU-E-J-92: CERR: New Tools to Analyze Image Registration Precision.

A Apte¹, Y Wang¹, J Oh¹

¹Memorial Sloan Kettering Cancer Center, New York, NY.

Medical Physics

|May 19, 2017

Summary

New tools in the Computational Environment for Radiotherapy Research (CERR) enhance image registration analysis. MirrorScope offers an intuitive visual method for assessing registration accuracy in radiotherapy research.

Keywords:

Computer software Databases Dosimetry Experiment design Image analysis Image registration Intensity modulated radiation therapy Medical imaging Mirrors Radiation therapy

More Related Videos

Picometer-Precision Atomic Position Tracking through Electron Microscopy

Picometer-Precision Atomic Position Tracking through Electron Microscopy

Published on: July 3, 2021

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

Published on: April 12, 2024

Related Experiment Videos

Last Updated: Mar 2, 2026

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Published on: October 27, 2023

Picometer-Precision Atomic Position Tracking through Electron Microscopy

Picometer-Precision Atomic Position Tracking through Electron Microscopy

Published on: July 3, 2021

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

Published on: April 12, 2024

Area of Science:

Radiotherapy research
Medical image analysis
Computational environments

Background:

The Computational Environment for Radiotherapy Research (CERR) is a widely cited platform for radiotherapy research.
Image registration is crucial for many radiotherapy research studies, including outcomes modeling and algorithm prototyping.

Purpose of the Study:

To introduce new software tools and updates within CERR.
To enhance the analysis of image registration accuracy and other research functionalities.

Main Methods:

CERR has been integrated with image registration frameworks (Plastimatch, ITK).
New analysis tools include Distance Discordance Histograms (DDH) and MirrorScope for evaluating registration accuracy.
Programmatic feature extraction and interfacing with statistical software (SPSS, Matlab) were implemented.

Main Results:

MirrorScope visually identifies accurate registrations through symmetric patterns.
Asymmetrical patterns in MirrorScope indicate regions of registration imperfection.

Conclusions:

CERR updates enhance its utility for radiotherapy research.
MirrorScope provides an intuitive and effective method for monitoring image registration accuracy, surpassing traditional visual methods.