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Updated: Mar 2, 2026
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Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
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Somatization in Parkinson's Disease: A systematic review
Danilo Carrozzino1, Per Bech2, Chiara Patierno3
1Psychiatric Research Unit, Psychiatric Centre North Zealand, Copenhagen University Hospital, Hillerød, Denmark; Department of Psychological, Health, and Territorial Sciences, University "G. d'Annunzio" of Chieti-Pescara, Chieti, Italy.
Summary
Somatization is common in Parkinson's Disease (PD), impacting cognitive decline. Further research is needed to understand its clinical effects and refine diagnostic approaches for this psychiatric symptom.
Area of Science:
- Neurology
- Psychiatry
- Psychosomatic Medicine
Background:
- Parkinson's Disease (PD) is a neurodegenerative disorder.
- Somatization, the expression of psychological distress through physical symptoms, is increasingly recognized in PD.
- Understanding the clinimetric implications of somatization in PD is crucial for patient care.
Purpose of the Study:
- To systematically review and critically analyze the clinimetric viewpoint of somatization's clinical consequence in Parkinson's Disease.
- To evaluate the prevalence and impact of somatization on cognitive function in PD patients.
Main Methods:
- Systematic literature review adhering to PRISMA guidelines.
- Comprehensive search across major scientific databases (e.g., PubMed, Scopus, Web of Science).
- Analysis of 9 relevant studies identified from an initial pool of 2,926 records.
Main Results:
- The prevalence of somatization in Parkinson's Disease ranges widely from 7.0% to 66.7%.
- Somatoform disorders significantly predict progressive cognitive impairment in PD patients.
- Somatization is a highly prevalent comorbidity in Parkinson's Disease.
Conclusions:
- Somatization is a significant and prevalent comorbidity in Parkinson's Disease.
- The clinical impact of somatization in PD warrants further investigation.
- Consideration of the psychosomatic concept of persistent somatization (DCPR) is recommended over 'psychogenic parkinsonism'.
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