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Related Concept Videos

Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

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DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
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Imaging Studies for Cardiovascular System III: X-Ray01:20

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The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
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Imaging Studies for Cardiovascular System V: CT01:28

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Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
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Imaging Studies for Cardiovascular System IV: CMRI01:21

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Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
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Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

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Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
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Imaging Studies for Cardiovascular System I:Echocardiography01:17

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Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
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Intravascular imaging in cardiovascular ageing.

Christos V Bourantas1, Tom Crake2, Yao-Jun Zhang3

  • 1Barts Heart Centre, Barts Health NHS Trust, London, UK; Institute of Cardiovascular Sciences, University College London, London, UK.

Experimental Gerontology
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Vascular ageing significantly impacts coronary artery disease by altering plaque morphology. Intravascular imaging reveals how these changes contribute to cardiovascular events, aiding in assessing atherosclerotic evolution.

Keywords:
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Area of Science:

  • Cardiovascular Medicine
  • Gerontology
  • Medical Imaging

Background:

  • Ageing involves molecular, inflammatory, and biochemical changes affecting coronary pathology.
  • Coronary artery disease and cardiovascular events are often consequences of these ageing-related changes.
  • Intravascular imaging is crucial for examining coronary plaque morphology and burden.

Purpose of the Study:

  • To review evidence from intravascular imaging studies on vascular ageing's impact on coronary artery morphology.
  • To discuss the role of coronary imaging in evaluating the progression of atherosclerosis.

Main Methods:

  • Systematic review of intravascular imaging studies.
  • Analysis of studies investigating vascular ageing mechanisms and plaque morphology.
  • Inclusion of studies comparing plaque pathology across age groups.
  • Examination of serial intravascular imaging data for atheroma burden and plaque composition changes.

Main Results:

  • Vascular ageing is associated with specific changes in coronary plaque morphology.
  • Intravascular imaging techniques demonstrate alterations in plaque burden and composition over time.
  • Differences in plaque pathology are observed between various age groups.

Conclusions:

  • Intravascular imaging provides valuable insights into the effects of vascular ageing on coronary arteries.
  • Coronary imaging holds potential for monitoring atherosclerotic evolution in ageing populations.