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Draft Genome Sequence of Staphylococcus epidermidis Clinical Strain GOI1153754-03-14 Isolated from an Infected Knee

Marta Bottagisio1,2, Alessio Soggiu2, Arianna B Lovati3

  • 1Cell and Tissue Engineering Laboratory, IRCCS Galeazzi Orthopedic Institute, Milan, Italy marta.bottagisio@grupposandonato.it.

Genome Announcements
|May 20, 2017
PubMed

Insights

We sequenced the genome of Staphylococcus epidermidis from an infected orthopedic implant. This provides insights into how bacteria form biofilms on medical devices.

Area of Science:

  • Microbiology
  • Genomics
  • Biomedical Engineering

Background:

  • Staphylococcus epidermidis is a common cause of orthopedic implant infections.
  • Biofilm formation by S. epidermidis on metallic implants leads to persistent infections.
  • Understanding biofilm mechanisms is crucial for preventing implant-associated infections.

Purpose of the Study:

  • To announce the draft genome sequence of a clinical Staphylococcus epidermidis strain (GOI1153754-03-14).
  • To provide genomic data for studying biofilm formation on orthopedic prostheses.

Main Methods:

  • Whole-genome sequencing of Staphylococcus epidermidis strain GOI1153754-03-14.
  • Bioinformatic analysis of the obtained genome sequence.

Main Results:

  • The draft genome sequence of S. epidermidis GOI1153754-03-14 is now available.
  • The genomic data offers a resource for investigating biofilm development.

Conclusions:

  • The genome sequence of this clinical strain will aid research into S. epidermidis biofilm formation.
  • This information can contribute to developing strategies against implant-associated infections.

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