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Draft Genome Sequence of the Tacrolimus-Producing Bacterium Streptomyces tsukubaensis F601
Gongli Zong1, Chuanqing Zhong2, Jiafang Fu1
1Shandong Academy of Medical Sciences, Shandong Medicinal Biotechnology Centre, Jinan, China.
Genome Announcements
|May 20, 2017
Abstract:
Streptomyces tsukubaensis strain F601 was found to be a producer of the immunosuppressive drug tacrolimus. The draft genome sequence of this strain was approximately 8.52 Mbp. Genes involved in the biosynthesis of tacrolimus were identified in the genome. This draft genome sequence will provide insights into the genetic basis of tacrolimus biosynthesis and regulation.

