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Published on: September 27, 2018
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Draft Genome Sequence of Mycobacterium abscessus Bamboo
Michelle Yee1, David Klinzing2, Jun-Rong Wei3,4
1Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore.
Genome Announcements
|May 20, 2017
Summary
Mycobacterium abscessus causes incurable lung disease and needs new drugs. This study provides a draft genome sequence for M. abscessus Bamboo, a strain useful for drug discovery.
Area of Science:
- Microbiology
- Genomics
- Drug Discovery
Background:
- Mycobacterium abscessus is an intrinsically multidrug-resistant pathogen.
- It causes chronic, incurable lung disease, representing an urgent unmet medical need.
- New therapeutic strategies are essential for combating M. abscessus infections.
Purpose of the Study:
- To report the draft genome sequence of M. abscessus Bamboo.
- To provide a valuable resource for drug discovery efforts against M. abscessus.
Main Methods:
- Genome sequencing of the clinical isolate M. abscessus Bamboo.
Main Results:
- A draft genome sequence of M. abscessus Bamboo has been generated.
- This sequence provides a foundation for understanding M. abscessus biology and resistance mechanisms.
Conclusions:
- The M. abscessus Bamboo genome sequence is a critical resource for developing novel antimicrobial agents.
- This work facilitates future drug screening and development for M. abscessus infections.
