[Psoriasis in 2016 : Co-morbidities and therapeutic update]

Area of Science:

• Dermatology
• Immunology
• Cardiovascular Medicine

Background:

• Psoriasis is increasingly recognized as a chronic systemic inflammatory condition.
• Established associations include joint involvement and depressive symptoms.
• Numerous studies highlight an elevated risk for comorbidities in psoriasis patients.

Purpose of the Study:

• To summarize the systemic implications of psoriasis.
• To underscore the association with comorbidities.
• To inform about the increased risk of cardiovascular events.

Main Methods:

• Literature review of studies on psoriasis and systemic conditions.
• Analysis of established associations and comorbidities.
• Synthesis of evidence regarding increased health risks.

Main Results:

• Psoriasis is linked to metabolic syndrome, obesity, hypertension, diabetes, and dyslipidemia.
• Non-alcoholic fatty liver disease and inflammatory bowel disease are associated with psoriasis.
• There is an increased incidence of cardiovascular events in patients with psoriasis.

Conclusions:

• Psoriasis management requires a systemic approach beyond skin symptoms.
• Early identification and management of comorbidities are crucial for psoriasis patients.
• Addressing systemic inflammation may reduce cardiovascular risk in psoriasis.