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Congenital Infantile Fibrosarcoma Associated With a Lipofibromatosis-Like Component: One Train May Be Hiding Another
Romain Swiadkiewicz1, Louise Galmiche, Kahina Belhous
1Departments of *Maxillofacial and Plastic Surgery, and †Pathology, Necker Children Hospital, APHP, Paris, France; ‡Paris Descartes University, Paris, France; Departments of §Pediatric Radiology, and ¶Dermatology, Necker Children Hospital, APHP, Paris, France; ‖Laboratory of Solid Tumors Genetics and Central Laboratory of Pathology, Nice University Hospital, Nice, France; **Microenvironment, Signaling and Cancer, INSERM, Université Nice Sophia-Antipolis, Nice, France; ††Molecular Oral Pathology, INSERM, Centre de Recherche de Cordeliers, Paris, France; and ‡‡Adolescent and Pediatric Oncology Department, Institut Curie, Paris, France.
Abstract:
Congenital infantile fibrosarcoma (CIFS) is a soft tissue sarcoma of infants mainly involving lower extremities and usually developing during the first year of life. At another end of the spectrum of pediatric fibroblastic lesions, lipofibromatosis is a rare benign infiltrative soft tissue tumor that affects children. The authors report in this study a particular presentation with a CIFS surrounded by lipofibromatosis-like areas. The presence of a surrounding benign tumor confused and delayed CIFS diagnosis.
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