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Published on: December 2, 2014
[Age aspects of arterial stiffness in patients with hypertension]
1Samara State medical university, Samara, 443099, Russian Federation; anatolii.rubanenko@gmail.com.
Insights
Arterial stiffness significantly increases in senior and elderly patients with hypertension. This age-related increase in arterial stiffness is linked to higher arterial stiffness index and augmentation index in older hypertensive individuals.
Area of Science:
- Cardiovascular Medicine
- Gerontology
- Hypertension Research
Background:
- Arterial stiffness is a key indicator of cardiovascular health.
- Hypertension is a major risk factor for increased arterial stiffness.
- Understanding age-related changes in arterial stiffness is crucial for managing cardiovascular risk.
Purpose of the Study:
- To investigate the relationship between age and arterial stiffness in patients with hypertension.
- To quantify age-related differences in arterial stiffness parameters.
Main Methods:
- Examined 130 hypertensive patients, divided into four age groups: young, middle-aged, senior, and elderly.
- Utilized standard ambulatory blood pressure monitoring.
- Analyzed the index of arterial stiffness and augmentation index.
Main Results:
- Senior and elderly hypertensive patients exhibited significantly increased arterial stiffness compared to younger patients.
- The index of arterial stiffness and augmentation index were notably higher in older hypertensive individuals.
Conclusions:
- Age is a significant factor contributing to increased arterial stiffness in hypertensive patients.
- Hypertension management strategies should consider age-related arterial stiffness changes, particularly in older populations.
Abstract:
To study age aspects of arterial stiffness we examined 130 patients with hypertension who signed protocol of informed consent to participate in research, mean age 61,7±14,3 years. All the patients underwent ambulatory blood pressure monitoring by the standard method and were divided into four groups: 1st group - patients of young age (n=17), 2nd group - patients of middle age (n=36), 3rd - senior patients (n=52), 4th - elderly patients (n=25). In senior and elderly patients with hypertension arterial stiffness significantly increases comparing with younger patients resulting in an increase of the index of arterial stiffness and augmentation index.
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