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Hypertension update, JNC8 and beyond

Tara Shrout1, David W Rudy2, Michael T Piascik3

  • 1The University of Kentucky College of Medicine, Class of 2018, NIH TL1 Training Program 2016-2017, USA.

Current Opinion in Pharmacology
|May 20, 2017
PubMed

Insights

This review compares hypertension guidelines from JNC 7 and JNC 8, highlighting controversial aspects of JNC 8. It explores suboptimal blood pressure control and potential solutions for better hypertension management.

Area of Science:

  • Cardiology
  • Clinical Guidelines
  • Public Health

Background:

  • Hypertension is a leading preventable risk factor for cardiovascular disease.
  • Effective treatment of hypertension reduces cardiovascular morbidity and mortality.
  • Clinical guidelines, such as JNC reports, guide hypertension management.

Purpose of the Study:

  • To compare the Joint National Committee (JNC) 7 and JNC 8 hypertension guidelines.
  • To critically evaluate the controversial aspects of the JNC 8 guidelines from a therapeutic standpoint.
  • To discuss recent evidence impacting JNC 8 recommendations and explore reasons for suboptimal blood pressure control.

Main Methods:

  • Comparative analysis of JNC 7 and JNC 8 guidelines.
  • Review of current scientific literature and evidence impacting hypertension management.
  • Exploration of therapeutic strategies and potential solutions for improving blood pressure control.

Main Results:

  • JNC 8 introduced modifications to JNC 7 regarding treatment thresholds, goals, and medication choices.
  • JNC 8 has generated significant controversy and debate within the medical community.
  • Blood pressure control rates remain suboptimal despite available guidelines.

Conclusions:

  • A thorough understanding of guideline differences and controversies is crucial for optimal hypertension care.
  • Addressing suboptimal blood pressure control requires exploring novel strategies like pharmacogenomics, risk stratification, lifestyle interventions, and integrative care.
  • Future research should focus on refining guidelines and implementing effective strategies to improve patient outcomes in hypertension management.

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