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PvGAMA reticulocyte binding activity: predicting conserved functional regions by natural selection analysis.

Luis A Baquero1, Darwin A Moreno-Pérez1,2, Diego Garzón-Ospina1,2

  • 1Molecular Biology and Immunology Department, Fundación Instituto de Inmunología de Colombia (FIDIC), Carrera 50 No. 26-20, Bogotá DC, Colombia.

Parasites & Vectors
|May 21, 2017
PubMed
Summary

Researchers identified key binding regions on Plasmodium vivax GPI-anchored micronemal antigen (PvGAMA). These conserved areas are crucial for parasite adhesion to reticulocytes, advancing understanding of malaria invasion.

Keywords:
Adhesin proteinConserved functional regionGenetic diversityPlasmodium vivaxReticulocyte binding activity

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