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A Simple Cell-based Immunofluorescence Assay to Detect Autoantibody Against the N-Methyl-D-Aspartate NMDA Receptor in Blood
Published on: January 9, 2018
[Autoimmune encephalitis associated to antibodies against the N-methyl-D-aspartate receptor: Report of two cases]
José Bustos1, Yasmin Sánchez, Jhon Medina
1Departamento de Neurología, Hospital San Rafael, Tunja, Colombia Escuela de Medicina, Facultad de Ciencias de la Salud, Hospital San Rafael, Tunja, Colombia. jose.bustos@uptc.edu.co.
Abstract:
Anti-N-methyl-D-aspartate receptor encephalitis is a neurological syndrome that is more common in young women and is often associated with ovarian teratoma. It is characterized by acute general unspecific symptoms that evolve to neurological deterioration, psychosis and seizures. In its more advanced stage it is associated with abnormal movements and dysautonomia.We report two cases in women of 23 and 12 years of age. Given its low incidence, we present the clinical exercise that led to their diagnoses and the treatment options employed.
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