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Precision Medicine: Genomic Profiles to Individualize Therapy
Oscar E Streeter1, Phillip J Beron2, Prashant Natarajan Iyer3
1The Center for Thermal Oncology, 2001 Santa Monica Boulevard, Suite 1190, Santa Monica, CA 90404, USA.
Precision medicine uses genetic and Omics biomarkers to personalize patient therapy. Understanding clonal mutations is key to predicting and managing treatment resistance through ongoing genetic analysis.
Area of Science:
- Biomedical Science
- Genomics
- Personalized Medicine
Background:
- Precision medicine leverages genotypic and Omics biomarkers for tailored, outcome-driven patient therapies.
- Healthcare institutions integrate extensive IT-enabled data, including imaging and electronic medical records, for treatment response assessment.
Purpose of the Study:
- To explore the role of genomic profiling in identifying therapeutic targets.
- To understand the implications of clonal mutational prevalence in treatment resistance.
Main Methods:
- Utilizing genotypic and Omics biomarkers for therapy selection.
- Integrating diverse data sources: imaging, electronic medical records, clinical sensors, and wearable devices.
- Employing genomic profiling to identify disease targets.
Main Results:
- Genomic profiling is continuously identifying new targets to influence disease progression.
- Understanding clonal mutational prevalence informs patients about common treatment resistance.
Conclusions:
- Precision medicine requires comprehensive data integration for optimal treatment selection.
- Ongoing genetic mutation collection is essential for managing and overcoming treatment resistance in patients.
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