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Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023
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Traumatic Brain Injury in the Workplace.
Michael Paci1, Claire Infante-Rivard2, Judith Marcoux1
11Department of Neurosurgery,Biostatistics and Occupational Health,McGill University,Montreal,Canada.
Summary
Hospitalized work-related traumatic brain injuries (TBIs) are often mild, predominantly affecting middle-aged men in construction. Despite most injuries being mild, some patients require neurosurgery, and a small percentage die, highlighting the need for improved safety measures.
Area of Science:
- Trauma surgery
- Neurology
- Occupational health
Background:
- Work-related traumatic brain injuries (TBIs) are under-documented, with existing studies lacking clinical detail.
- Previous research often relies on worker databases, which do not capture crucial patient information.
Purpose of the Study:
- To characterize hospitalized patients diagnosed with work-related TBIs.
- To describe the clinical profiles and outcomes of individuals with occupational TBIs.
Main Methods:
- Utilized Québec provincial trauma and TBI program databases (2000-2014).
- Extracted data from medical records of patients admitted to a level 1 trauma center.
- Employed descriptive statistics to summarize patient characteristics and injury patterns.
Main Results:
- Analyzed 285 cases of work-related TBI.
- Patients were middle-aged (mean 43.6 years), predominantly male (18:1 ratio), and often from the construction industry.
- Falls were the most common cause; 76.8% had mild TBI, 14% needed neurosurgery, and 8.1% died. Skull fractures were common on CT scans.
Conclusions:
- Most work-related TBIs are mild, but some necessitate neurosurgical intervention, and mortality is non-negligible.
- Enhanced fall prevention and safety practices, particularly in construction, are crucial.
- Accurate documentation of helmet use could aid in reducing the burden of occupational TBIs.

