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Updated: Mar 2, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Secondary Skin Plasmacytomas
Pedro Mendes-Bastos1, Susana Brás2, Cristina Amaro2
1Department of Dermatology and Venereology, Hospital de Curry Cabral, Centro Hospitalar de Lisboa Central, Lisbon, Portugal; pmendesbastos@gmail.com.
Abstract:
A 78-year old man was diagnosed in 2006 with IgAκ multiple myeloma (MM) (stage III-A). The patient was referred to our dermatology department in 2012 for evaluation of erythematous skin nodules on the anterior right aspect of the thorax; the skin lesions were noted during hospitalization for multiple bone fractures. He was on fourth-line chemotherapy (with vincristine/adriamycin/dexamethasone) because of constant disease progression. The patient was unaware of the skin lesions' evolution over time and did not recall when they had first appeared. He had no pain, itching, or spontaneous bleeding.
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