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Depressive Status in Patients With Chronic Thromboembolic Pulmonary Hypertension

Sayaka Funabashi1, Masaharu Kataoka2, Takumi Inami1

  • 1Second Department of Internal Medicine, Kyorin University School of Medicine.

Circulation Journal : Official Journal of the Japanese Circulation Society
|May 23, 2017
PubMed

Insights

Patients with chronic thromboembolic pulmonary hypertension (CTEPH) experience higher depressive status and possess a depressive temperament compared to healthy individuals. Future research will explore the link between CTEPH biological traits and this temperament.

Area of Science:

  • Cardiology
  • Psychiatry
  • Pulmonary Medicine

Background:

  • Chronic thromboembolic pulmonary hypertension (CTEPH) is a condition affecting pulmonary arteries.
  • The psychological impact, specifically depressive status and temperament, in CTEPH patients remains under-investigated.
  • Comparative studies are essential to understand psychological differences between CTEPH patients and healthy populations.

Purpose of the Study:

  • To investigate and compare the depressive status of patients diagnosed with CTEPH against healthy volunteers.
  • To assess and compare the inherent temperament of CTEPH patients with that of healthy individuals.
  • To establish a baseline for understanding the psychological profile associated with CTEPH.

Main Methods:

  • A comparative study design was employed.
  • Participants included patients diagnosed with CTEPH and a control group of healthy volunteers.
  • Standardized psychological assessments, including temperament and personality scales and the Quick Inventory of Depressive Symptomatology-Self Report, were utilized.

Main Results:

  • CTEPH patients exhibited a significantly higher prevalence of depressive symptoms compared to healthy volunteers.
  • Analysis of temperament and personality scales indicated a distinct psychological profile in CTEPH patients.
  • The Quick Inventory of Depressive Symptomatology-Self Report scores were notably elevated in the CTEPH cohort.

Conclusions:

  • CTEPH patients demonstrate a significantly increased depressive status relative to healthy individuals.
  • A potentially inherent depressive temperament may be associated with the origin of CTEPH.
  • Further research is warranted to elucidate the interplay between biological factors of CTEPH and depressive temperament.
Abstract

Keywords:
Chronic thromboembolic pulmonary hypertensionComparative studyDepressive status

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