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Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
Published on: October 14, 2021
[PURPURIC MYCOSIS FUNGOIDES]
Boaz Amichai1,2, Boaz Gabay1,2, Mario Cordoba3,2
1Dermatology Unit, Meir Medical Center, Kfar-Saba.
Introduction:
A 26-year-old female presented with 4-years duration of asymptomatic spots on her left leg. She was otherwise healthy. On examination several purpuric patches up to 3 cm. in diameter were found on the flexure aspect of her left leg. Histological examination revealed lymphocytic infiltrate, with mild atypia, with red blood cell extravasation and hemosiderin deposition in the papillary dermis. The clinical and histological findings were compatible with the diagnosis of early stage purpuric mycosis fungoides (MF). Purpuric form of MF is a rare form of the disease. Physician should distinguish this disease from benign forms of pigmented purpuric dermatoses.
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