Related Experiment Video
Updated: Mar 2, 2026

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
Published on: October 14, 2021
[PURPURIC MYCOSIS FUNGOIDES]
Boaz Amichai1,2, Boaz Gabay1,2, Mario Cordoba3,2
1Dermatology Unit, Meir Medical Center, Kfar-Saba.
This case study highlights an early-stage purpuric mycosis fungoides (MF) presentation, a rare skin condition. Distinguishing this from benign pigmented purpuric dermatoses is crucial for accurate diagnosis and treatment.
Area of Science:
- Dermatology
- Oncology
Background:
- Presents a rare case of purpuric mycosis fungoides (MF).
- Discusses the diagnostic challenges in differentiating MF from benign conditions.
Observation:
- A 26-year-old female with a 4-year history of asymptomatic purpuric patches on her left leg.
- Clinical presentation included purpuric patches up to 3 cm on the flexure aspect of the leg.
Findings:
- Histological examination revealed lymphocytic infiltrate with mild atypia.
- Evidence of red blood cell extravasation and hemosiderin deposition in the papillary dermis confirmed the diagnosis.
Implications:
- Emphasizes the importance of recognizing early-stage purpuric mycosis fungoides.
- Underscores the need for clinicians to differentiate this rare MF variant from benign pigmented purpuric dermatoses to ensure appropriate patient management.
More Related Videos
08:17A Human Peripheral Blood Mononuclear Cell PBMC Engrafted Humanized Xenograft Model for Translational Immuno-oncology I-O Research
Published on: August 15, 2019
06:15Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Related Concept Videos
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...