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[THE ISRAELI RAT GENOME CENTER]
1The Israeli Rat Genome Center, Barzilai Medical Center Campus, Faculty of Health Sciences of the Ben-Gurion University of the Negev, Ashkelon.
Harefuah
|May 23, 2017
Summary
The Israeli Rat Genome Center offers unique rat models for complex diseases like hypertension and diabetes. These genetic resources are available for collaborative research worldwide to advance understanding of these conditions.
Area of Science:
- Genetics
- Animal Models
- Complex Diseases
Background:
- Established the Israeli Rat Genome Center to house unique rat strains developed in Israel.
- The Center provides models for salt-sensitive hypertension, type 2 diabetes, and combined hypertension-diabetes.
- Offers additional genetic strains including transgenics, consomics, and congenics.
Purpose of the Study:
- To provide a repository of unique rat genetic strains simulating complex human diseases.
- To make these specialized rat models available to the global research community for collaborative studies.
- To conduct independent research on the genetic underpinnings of hypertension, diabetes, and related conditions.
Main Methods:
- Development and maintenance of specialized rat genetic strains.
- Distribution of unique rat models to researchers worldwide.
- Conducting molecular medicine research on complex diseases.
Main Results:
- A repository of unique rat strains for hypertension, diabetes, and other complex diseases has been established.
- These models are accessible to researchers for collaborative disease study.
- Independent research is ongoing into the genetic basis of hypertension, diabetes, and cardiovascular/metabolic diseases.
Conclusions:
- The Israeli Rat Genome Center serves as a vital resource for studying complex diseases using specialized rat models.
- Collaboration and accessibility of these unique strains facilitate global research efforts.
- The Center's research contributes to understanding the genetic basis of major health challenges.