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Association of dietary factors with severity of coronary artery disease

Namita Mahalle1, M K Garg2, S S Naik1

  • 1Deenanath Mangeshkar Hospital and Research Center, Biochemistry Section, Department of Pathology, Erandawane, Pune 411004, India.

Clinical Nutrition ESPEN
|May 23, 2017
PubMed

Insights

Dietary habits significantly impact coronary artery disease (CAD) severity. Lower intake of protein, fiber, vitamins, and minerals, alongside higher carbohydrate intake, correlates with more severe CAD in Indian patients.

Area of Science:

  • Cardiology
  • Nutritional Science
  • Public Health

Background:

  • Cardiovascular disease (CVD) prevalence has surged globally.
  • Cardiovascular risk factors exacerbate coronary lesion progression and patient prognosis.
  • This study investigated dietary factors' link to coronary artery disease (CAD) severity in an Indian cohort.

Purpose of the Study:

  • To analyze the association between dietary patterns and the severity of coronary artery disease (CAD).
  • To identify specific nutritional components influencing CAD progression in Indian patients.

Main Methods:

  • Included 300 patients aged over 25 with diagnosed coronary artery disease.
  • Assessed CAD severity by the number of diseased vessels: single (SVD), double (DVD), or triple (TVD).
  • Collected blood samples for biochemical markers and analyzed dietary intake.

Main Results:

  • Triple-vessel disease (TVD) patients exhibited higher BMI, triglycerides, insulin resistance, and hsCRP, with lower HDL cholesterol.
  • TVD prevalence was higher among patients with diabetes, hypertension, and dyslipidemia.
  • Increased CAD severity correlated with higher carbohydrate intake, lower protein and fiber intake, and reduced intake of essential vitamins and minerals. Palmitic acid intake was higher in TVD patients.

Conclusions:

  • Dietary factors are significantly associated with coronary artery disease severity.
  • Lower intake of protein, fiber, vitamins, and minerals, coupled with higher carbohydrate consumption, increases the likelihood of severe CAD.
Abstract

Keywords:
Coronary artery diseaseDietary factorsSeverity

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