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Updated: Mar 2, 2026

FISH for Pre-implantation Genetic Diagnosis

FISH for Pre-implantation Genetic Diagnosis

Published on: February 23, 2011

Preconception and prenatal genetic counselling.

Adonis S Ioannides¹

¹University of Nicosia Medical School, 93 Agiou Nikolaou Street, Engomi P.O. Box 24005, 1700 Nicosia, Cyprus.

Best Practice & Research. Clinical Obstetrics & Gynaecology

|May 24, 2017

Summary

Genetic screening for prospective parents informs reproductive decisions and can reduce the incidence of genetic conditions. Advances in genomic technology offer expanded screening, but further research is needed for optimal application.

Keywords:

folic acid genetic counselling genetic testing mass screening preconception care prenatal care

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Area of Science:

Reproductive genetics
Medical screening
Genomic technologies

Background:

Genetic counselling informs reproductive choices for conditions and anomalies.
Preconception and prenatal stages are key for risk identification.
Carrier screening for diseases like beta thalassaemia has proven effective.

Purpose of the Study:

To explore the expanded scope of genetic screening using new genomic technologies.
To provide comprehensive information to prospective parents regarding genetic risks.
To discuss the implications of advanced genetic screening in reproductive health.

Main Methods:

Review of current genetic screening practices.
Analysis of advances in genomic technologies for expanded screening.
Discussion of the role of preconception counselling and carrier screening.

Main Results:

Genomic technologies enable broader genetic screening for prospective parents.
Early identification of genetic risks allows for informed reproductive decisions.
Established screening methods, like for beta thalassaemia, have reduced disease incidence.

Conclusions:

Expanded genetic screening through new technologies offers comprehensive parental information.
Further research is essential to determine the best use of these advanced genomic tools.
Integrating new genomic screening into general practice requires careful consideration and evidence.